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Programme for Elimination of Lymphatic Filariasis in the World Health
Organization African Region: Implementation Update as of October 2003
(page 2)
The expansion
of mapping in the WHO African region prioritizes 1) completion of mapping
in those countries that have started MDA (treating Nigeria and Tanzania
as exceptional cases that will continue mapping up to 2005), 2) extending
mapping to countries neighbouring those already carrying out MDA, and
3) the island nations that have not yet been involved in any LF programme
activities (other than Comoros which is already implementing the MDA)
are in the last group of countries to be mapped together with those
countries isolated from other endemic areas. This plan was developed
to promote effectiveness of the MDA on interruption of transmission
by having geographically contiguous areas treated within the same period.
However, this plan is flexible to accommodate preferences of partners
who may wish to support a specific country at any time.
MDA has progressed from 4 countries in 2000 to 9 countries in 2002.
MDA implementation status as of December is shown in figure 3. 
Fig. 3: LF MDA implementation status as of December 2003
To date, no additional countries have implemented MDA due to insufficient
funding and technical problems encountered with the diagnostic kit used
to map LF, which created an interruption in mapping. It is, however,
noteworthy that although 9 countries are implementing MDA, only the
programmes in Comoros, and Togo are currently covering the entire at-risk
population. Rapid scaling up in the remaining countries to reach national
scale is a priority and highly desirable. The current status of mapping
and MDA implementation in the WHO African Region is shown in figure
4.
Fig. 4: Status of LF mapping and MDP implementation in the WHO African
Region
Rapid
expansion in geographical coverage both within the countries and in
the region as a whole, is one of the major priorities of the programme;
the other is achievement of high therapeutic coverage during the MDA
campaigns. In 2002, 9,956,118 people were treated against a regional
annual treatment objective (RATO) of 16.1 million representing 60% of
the RATO. For 2003, tentative figures indicate that 17,071,155 have
been treated against a RATO of 21.6 million, which represents 79% of
the set RATO. Based on the 2002 MDA, national average figures of reported
therapeutic coverage rates range from 56.8% in Comoros to 83.1% in Zanzibar,
Tanzania. The lowest coverage rate obtained in an IU is 49.7% and the
highest is 92.7% (both figures from the Ghana programme). There are
exceptional observations in Nigeria where the range is 59.8 - 153.1%.
Coverage rates higher than 85% indicate treatment of populations external
to the implementation unit that are untracked and/or some national programmes,
are using the eligible population instead of the population at risk
as the denominator to calculate therapeutic coverage in the IU. This
may be true to varying extents in many of the national programmes and
it is an important confounder during monitoring and evaluation of the
impact of MDA. Coverage rates that are well below the 65% minimum determined
for effective impact on transmission remain a major concern as these
treatment rounds might as well be disregarded since they are likely
to have a negligible effect on community parasite loads. Factors contributing
to low therapeutic coverage reported by most countries include 1) lack
of motivation of drug distributors, 2) refusals (noncompliance), 3)
inadequate or delayed information, education and communication (IEC)
materials, and 4) heavy workloads.
Conclusion
Assessment of disease burden, specifically the population at risk, is
on course and will meet the set target of 2005. Results of mapping, from
the group of countries that have either completed the exercise or are
in the process, reveal that the population at risk may be higher than
currently estimated due to the fact that some areas that appear ecologically
non-endemic have been found to be endemic. For example, Burkina Faso is
wholly endemic despite the fact that a large proportion of the country
is dry and lacks suitable breeding grounds for the vector. The major challenge
to the programme remains insufficient financial resources for mapping
and to support drug delivery activities. Mapping and drug delivery remain
the biggest challenges in Nigeria and to a lesser extent in Tanzania and
The Democratic Republic of Congo, these being the largest and/or most
populated LF-endemic countries in the WHO African Region. Finally, it
is recommended that all countries implementing MDA use the total population
of IUs instead of the eligible population as the denominator for the computation
of therapeutic coverage.
By:
Dr. Jean Baptiste Roungou, Dr. Likezo Mubila, Mr. Ekoue Kinvi, Mr. Adolphe
Dabire
Other Tropical Diseases Unit
Division of Prevention and Control of Communicable Diseases
WHO African Region |